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Fabry disease is an X-linked recessive inborn metabolic disorder in which a deficiency in lysosomal enzyme alpha-galactosidase A Gal A causes the systemic accumulation of globotriaosylceramide Gb3. Although many investigators have attempted to treat alpha-Gal A knock-out mice Fabry mice with gene therapy, no report has demonstrated therapeutic effects by the retrograde renal vein injection of naked DNA. We recently developed a naked plasmid vector-mediated kidney-targeted gene transfer technique. We confirmed that vector-derived human alpha-Gal A mRNA was present in the left kidney but not in other tissues, by reverse transcriptase polymerase chain reaction.
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By Tyler J Stewart. Installation view at the Southern Alberta Art Gallery. But here I am: naked, with the artist on the other side of the door guarding my privacy. My emotions swing from trepidation, nervousness, and shame, to confusion, excitement, enchantment, peacefulness, and—by the end of my visit to the gallery—serenity. Working to activate and free all modes of sensation, the exhibition is woven with a buzzing undercurrent of magic. Lightboxes, rugs, photographic prints, encaustic painting, and sculptures positioned around the room stand not just as objects, but as perceptual portals through which I find myself transcending the physical space.
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VI. Requiem for a Revolution?

With each Summer and Winter season no less than 15 colors are added to our range. Quantity Discount combination of different collections possible. For best results N Naked Beauty , it is recommended to do a dry manicure not soaking the hands and nails in water prior to application. Allow GEL. Non Wipe Top Coat.
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